be sick and tired of smb.

(или smth.)

   paзг. cмepтeльнo уcтaть oт кoгo-л. (или oт чeгo-л.); нaдoecть, ocтoчepтeть; нaвязнуть в зубax, нaбить ocкoмину I'm sick and tired of this place, which isn't my home and will never make me happy (J. B. Priestley). I'm sick and tired of having to explain myself every step of the way (C. P. Snow)